Thursday, 29 May 2025

Artificial Intelligence (AI) in Healthcare and beyond

An RSC Café Chimique on Artificial Intelligence (AI) took place on Tuesday 13 May 2025 in the Social Area above the Brel Theatre at the British School of Brussels. Our two speakers were pioneering entrepreneurs of the use of AI in healthcare: Dr Dani Manjah from Professor Benoit Macq's research group at the Ecole Polytechnique de Louvain, and Thibaut Helleputte, founder and CEO of DNAlytics, a start-up specialising in data sciences applied to healthcare located in Louvain-la-Neuve.

The debate was chaired by Professor Bob Crichton, our recent past Chair of the section and the discussion was kicked off, as usual for our Cafe Chimique events, by short presentations from the two speakers.

Our first presentation was from Dani who gave a quick overview of what AI was - and was not - and then described some applications in healthcare. Dani's presentation is embedded below.


Thibaut then gave some further insights to his work on AI and healthcare. His presentation is embedded below as a pdf.


Following the two presentations an extensive and wide-ranging discussion was initiated led by questions from the audience. Issues covered included societal and socio-economic issues as well as sector-specific concepts.

As with our previous debates the audience was seated in a café-style format and gratis drinks and light refreshments were available before and during the event.

Strange Ice

On the evening of Thursday 27 March 2025, the section welcomed Professor Andrea Sella of University College London back to Belgium to give us his 'Strange Ice' talk. The talk was a highly personal journey into the world of the strange solid that all of us know and love and yet which conceals deep mysteries and dark prophecies about our shared future. 

Andrea's presentation took us from a glass of water to the skies above our heads, from the Alps to the winters of Poland and up to the Arctic, stopping to look at a variety of other ices, both crystalline and amorphous, and asking questions about chemistry, physics, psychology, climate change, disinformation and politics. Ice speaks. Can we learn to listen?

The talk was highly informative, entertaining and thought provoking and initiated a wide-ranging discussion that continued into the post-talk networking. 

A video of the proceedings was recorded and will be available soon on the RSC Belgium YouTube channel and is also embedded below.

[VIDEO TBC]

 About Andrea

Andrea Sella is a chemist and broadcaster based at University College London where he is a Professor of Inorganic Chemistry. His main research is on rare-earth metals and he collaborates with several research groups on hydrogen storage, carbonitrides, and nanotube insertion chemistry. He has been involved in numerous television documentaries, including the 2010 BBC documentary “Chemistry: A Volatile History”, which was nominated for the 2010 British Academy Television Awards. In 2014 he presented "My Family and other Ibex" and "Urine Trouble: What's in our Water" on BBC Radio 4. He has been a guest on Melvyn Bragg's “In Our Time” and appeared regularly on radio programmes like Start the Week, Weekend, Newshour, the Today Programme and the Infinite Monkey Cage. He has been consultant and contributor for the BBC World Service's series "Elemental Economics" presented by Justin Rowlatt.

Andrea had previously presented our 2010 demonstration lectures, as part of the annual ‘Printemps des Sciences’ festival in March at Louvain-la-Neuve. On that occasion (pre blog) he gave us a fascinating exposition on oscillating reactions somewhat confusingly called ‘How the Zebra got its Stripes’ - and had delivered one of the lectures in French.

Wednesday, 28 May 2025

ICP-mass spectrometry in the biomedical sciences: pushing the boundaries of the application range

On the evening of Tuesday 29 April the section welcomed Professor Frank Vanhaecke from Ghent University to talk about ‘ICP-mass spectrometry in the biomedical sciences: pushing the boundaries of the application range’. Frank received the Royal Society of Chemistry’s prestigious ‘Theophilus Redwood award’ in 2023 for outstanding contributions to the chemical sciences in the area of analytical chemistry. 

Frank's talk discussed recently developed analytical methodology including the use of laser ablation – ICP-MS to reveal the distribution of (trace) elements across biological tissues, the determination of metal contents in individual cells and the use of metal isotope ratios for diagnostic and prognostic purposes.

Inductively coupled plasma-mass spectrometry (ICP-MS) is the most powerful tool for trace element analysis, as a result of which it is widely used in many application areas, including clinical analysis. While in clinical analysis, determination of essential and non-essential (toxic) elements in body fluids and tissues is considered a routine application, other approaches have not reached that status yet, despite their added value.

Frank showed how through the use of laser ablation (LA) as a means of sample introduction, a thin section of tissue can be interrogated point-by-point to reveal the distribution of targeted elements in a quantitative manner. Moreover, when combining LA with an ICP-MS unit equipped with a time-of-flight (ToF) mass analyser, a nearly complete elemental mass spectrum is available for every pixel on the tissue “map”.

The detection power of ICP-MS instrumentation has meanwhile been enhanced to such an extent that it also allows quantification of the content of exo- and endogenous elements in individual cells, using either traditional pneumatic nebulization or laser ablation as a means of sample introduction.

In addition, Frank showed how high-precision isotopic analysis of essential mineral elements can provide insights into biochemical processes and diagnostic/prognostic information, as isotope ratios can pick up on metabolic changes with higher sensitivity than element concentrations can and/or provide information that is not embedded in the element concentrations.

The added value of these more novel approaches was illustrated by discussing the results of a number of interdisciplinary research projects carried out at Frank’s labs in Ghent.

A video of Frank's presentation is embedded below or can be viewed on the RSC Belgium dedicated YouTube channel.

About Frank

Frank Vanhaecke is Senior Full Professor in Analytical Chemistry at Ghent University, where he also leads the Atomic & Mass Spectrometry  (A&MS) research group that specialises in the determination, speciation and isotopic analysis of (ultra)trace elements via ICP-MS. His group studies fundamental aspects of the technique and develops methods for solving challenging scientific problems in interdisciplinary contexts. Frank is (co)author of more than 500 papers and the work of his has team received a number of prestigious awards, including the RSC’s ‘Theophilus Redwood award’ in 2023.