Iron Age weapons join the fight against Antimicrobial resistance

On the evening of Tuesday 15 October, RSC Belgium welcomed Professor Ricardo Louro who is head of the Inorganic Biochemistry and the NMR laboratory at ITQB-NOVA – an interdisciplinary research and advanced training institute of NOVA University in Lisbon, Portugal - to talk to us about antimicrobial resistance (AMR), which is an emerging concern that is threatening to burst the antibiotic bubble that has kept us largely safe from bacterial infection for nearly eight decades since the discovery of penicillin by Alexander Fleming.

It is estimated that AMR directly caused over 1.2 million deaths globally in 2019 and was a contributing factor in just under 5 million more. Without immediate global action, AMR could lead directly to over 8.2 million deaths each year by 2050 overtaking cancer as the primary cause of death.

A new global initiative to tackle AMR was launched in September this year at the United Nations General Assembly. The UN commitment aims to strengthen efforts to combat AMR and sets important targets, such as cutting global AMR-related deaths by 10% by 2030 and developing national action plans. Additional goals include reducing the use of antibiotics in agriculture and ensuring that low- and middle-income countries receive adequate financial support to fight AMR.

Professor Louro presented the problem, described current antibiotic targets and argued that scientific discoveries are uncovering new targets that have the potential to preserve our protection from bacterial infections into the future. In particular he focused on the emergence of  “Iron age weapons” that can help us to fight AMR by interfering with the iron metabolism of the target bacteria.

The talk, which took place at the British School of Brussels in Tervuren, was followed by a lively Q&A session that extended into our usual networking social event afterwards.

YouTube Video

Ricardo's excellent talk on AMR was recorded and can be found on our dedicated Youtube channel or as an embedded video below. Enjoy!