New Horizons in synthesis: click chemistry and beyond

On the evening of Thursday 20 April from 19h30 RSC Belgium welcomed Professor Ari Koskinen, Emeritus Professor of Organic Chemistry at Aalto University, Finland to talk to us about ‘New Horizons in synthesis: click chemistry and beyond’. The event was held at the British School of Brussels in Tervuren and was followed by an opportunity for RSC members and friends to network and ask informal questions of the speaker over drinks and snacks.

A central feature of chemistry is to produce novel connections between atoms, in other words chemical synthesis. The state of the art of organic chemical synthesis is defined by the complexity of the target structures one can produce in an efficient manner. Especially during the past two decades, different economies of synthesis have taken a central role in the development of synthetic chemical strategies. Thus atom economy, step economy, redox economy are valid targets for synthesis research.

‘Click chemistry’ and biorthogonal chemistry are timely subjects and Ari took us through a brief history of organic synthesis and introduced us to the latest trends in this important part of chemistry. 

The 2022 Nobel Prize in Chemistry was awarded to Carolyn Bertozzi, Morten Meldal, and Barry Sharpless for the development of click chemistry and bioorthogonal chemistry.

As usual, the session was recorded and you can access it direct via the RSC YouTube channel here or via the embedded video below.

Our speaker

Professor Ari Koskinen (pictured below) received his M.Sc. (Chem. Eng.) in 1979, his Licentiate in Technology in 1982 and his Doctor of Technology in 1983 from the Helsinki University of Technology.

After postdoctoral studies at the University of California, Berkeley he accepted an appointment as a Project Leader in New Drug Development at Orion Corporation – Fermion, Finland where his research group was among the first in Scandinavia to adopt computer aided drug design as well as computerized database handling protocols in new lead identification. Returning to academia, he joined the University of Surrey as a lecturer in 1989 and was then appointed as Professor of Chemistry (especially Synthetic Organic Chemistry) at the University of Oulu, Finland in 1992, and transferred to the Helsinki University of Technology in 1999 (Aalto University since 2010) as Professor of Organic Chemistry.

Prof. Koskinen is a member of the Finnish Academy of Sciences and Letters since 2003. He is the author or co-author of some 190 publications, 15 patents and three books. He retired from active academic work in October 2021, but as emeritus professor, he keeps his finger on the pulse of organic chemistry through activities in IUPAC (Division of Organic and Biomolecular Chemistry) and EuChemS (secretary, Division of Organic Chemistry).